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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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LY2886721

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Cat No.

CEI-0704

Description

Cell-permeable. A potent and selective β-secretase (BACE-1) inhibitor (IC50 = 20 nM for recombinant hBACE1). Does not inhibit other aspartyl proteases such as cathepsin D, pepsin, and renin. A potential agent to treat Alzheimer’s Disease.

Appearance

White solid

Product Overview

A potent selective β-secretase (BACE-1) inhibitor.

CAS No.

1262036-50-9

Molecular Weight

110.1

Purity

>99% by HPLC

Storage

Targets

BACE1

Molecular Formula

C 18 H 16 F 2 N 4 O 2 S

Chemical Name

N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide

Solubility

H₂O (100 mM)

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