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LY2886721
Cat No.
CEI-0704
Description
Cell-permeable. A potent and selective β-secretase (BACE-1) inhibitor (IC50 = 20 nM for recombinant hBACE1). Does not inhibit other aspartyl proteases such as cathepsin D, pepsin, and renin. A potential agent to treat Alzheimer’s Disease.
Appearance
White solid
Product Overview
A potent selective β-secretase (BACE-1) inhibitor.
CAS No.
1262036-50-9
Molecular Weight
110.1
Purity
>99% by HPLC
Storage
RT
Targets
BACE1
Molecular Formula
C 18 H 16 F 2 N 4 O 2 S
Chemical Name
N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide
Solubility
H₂O (100 mM)
Shipping Conditions
RT
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