Linaclotide, also known as linaclotide acetate, trade name Linzess, is a synthetic peptide structure containing 14 amino acids related to the endogenous guanylyl peptide family, and is the only FDA-approved clinically available intestinal locally-activated GC-C (guanylate cyclase-C) agonist analog for the treatment of constipated irritable bowel syndrome (IBS-C) and chronic idiopathic constipation ( CIC) adult patients.
Applications
For the treatment of constipated irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC).
Package
50G/Bottle or at customers reqirement.
CAS No.
851199-59-2
Molecular Weight
1525.39Da
Storage
-25~-15°C
Molecular Formula
C59H79N15O21S6
Amino Acid Sequence
H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH(Disulfide bond Cys1&Cys6，Cys2&Cys10，Cys5&Cys13)
Download Datasheet