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leukotriene-A4 hydrolase
Cat No.
EXWM-4003
Description
This is a bifunctional zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities. It preferentially cleaves tripeptides at an arginyl bond, with dipeptides and tetrapeptides being poorer substrates (see EC 3.4.11.6, aminopeptidase B). It also converts leukotriene A4 into leukotriene B4, unlike EC 3.3.2.10, soluble epoxide hydrolase, which converts leukotriene A4 into 5,6-dihydroxy-7,9,11,14-icosatetraenoic acid. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol-5,6-oxide hydrolase).
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
90119-07-6
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase
Reaction
leukotriene A4 + H2O = leukotriene B4
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0419 | Leukotriene A4 Hydrolase from Human, Recombinant | EC 3.3.2.6 | 90119-07-6 | E. coli | Inquiry |