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Lestaurtinib
Cat No.
CEI-0484
Description
An indolocarbazole derivative with antineoplastic properties. Acts as a potent inhibitor of several tyrosine kinases including FLT3, JAK2, and TrkA with IC50 values of 3, 1, and <25 nM, respectively. It suppresses JAK2/STAT5 signaling and is effective against myeloproliferative disorders in vivo.
Alias
CEP-701; KT-5555; SPM-924
Appearance
White solid
Product Overview
A PTK inhibitor
CAS No.
111358-88-4
Molecular Weight
1009.17
Purity
>98%
Storage
-20 centigrade
Synonyms
CEP-701; KT-5555; SPM-924
Targets
FLT3, JAK2, NTRK1
Molecular Formula
C26H21N3O4
Solubility
DMSO or EtOH
Shipping Conditions
RT
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