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leishmanolysin
Cat No.
EXWM-4318
Description
A membrane-bound glycoprotein found on the promastigote of various species of Leishmania protozoans. Contains consensus sequence for a zinc-binding site; Z-Tyr-Leu-NHOH is a strong inhibitor. The enzyme can activate its proenzyme by cleavage of the Val100┼Val bond. An acid pH optimum is found with certain protein substrates. Type example of peptidase family M8
Form
Liquid or lyophilized powder
Enzyme Commission Number
EC 3.4.24.36
CAS No.
161052-06-8
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
promastigote surface endopeptidase; glycoprotein gp63; Leishmania metalloproteinase; surface acid proteinase; promastigote surface protease
Reaction
Preference for hydrophobic residues at P1 and P1' and basic residues at P2' and P3'. A model nonapeptide is cleaved at -Ala-Tyr┼Leu-Lys-Lys-
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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