Mammalian lactate dehydrogenases (LDH) exist as five tetrameric isozymes composed of combinations of two different subunits. The H subunit predominates in heart muscle, which is geared for aerobic oxidation of pyruvate. The M subunit predominates in skeletal muscle and is concerned more with anaerobic metabolism and pyruvate reduction.
Source
E. coli
Species
Rabbit muscle
Form
Lyophilized powder
Enzyme Commission Number
EC 1.1.1.27
Activity
≥250 units per mg protein
CAS No.
9001-60-9
Unit Definition
One Unit oxidizes one micromole of NADH per minute at 25°C, pH 7.3.