Description
Ki20227, a c-fms tyrosine kinase inhibitor, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model.
Alias
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Product Overview
c-fms tyrosine kinase inhibitor
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Molecular Formula
C24H24N4O5S
Chemical Name
(N-{4-[(6,7-dimethoxy-4-quinolyl)oxy]-2-methoxyphenyl}-N'-[1-(1,3-thiazole-2-yl)ethyl]urea)
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL