Description
A selective inhibitor of soluble adenylyl cyclase (sAC) ( IC50 = 3-10 µM in vivo). Displays little effect on transmembrane adenylyl cyclases. KH7 is not active against sAC in the presence of detergents. At concentrations above 50 µM, KH7 exhibits non-specific membrane disruption effects when used on cells.
Product Overview
A selective inhibitor of soluble adenylyl cyclase (sAC)
Molecular Formula
C 17 H 15 BrN 4 O 2 S
Chemical Name
2-(1H-benzimidazol-2-ylthio)-2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide, propanoic acid
Solubility
DMSO (~25 mg/ml)
Shipping Conditions
Gel pack
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