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JK 184

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Cat No.

CEI-0450

Description

An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Al dh7) (IC50 = 210 nM).

Appearance

White solid

Product Overview

A hedgehog(Hh) signaling pathway antagonist

CAS No.

315703-52-7

Molecular Weight

255.23

Purity

>98% by HPLC

Storage

+4 centigrade

Targets

ADH7

Molecular Formula

C₁₉H₁₈N₄OS

Chemical Name

N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine

Solubility

DMSO (~5 mg/ml) or H2O (~ 5 mg/ml)

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