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JK 184
Cat No.
CEI-0450
Description
An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Al dh7) (IC50 = 210 nM).
Appearance
White solid
Product Overview
A hedgehog(Hh) signaling pathway antagonist
CAS No.
315703-52-7
Molecular Weight
255.23
Purity
>98% by HPLC
Storage
+4 centigrade
Targets
ADH7
Molecular Formula
C₁₉H₁₈N₄OS
Chemical Name
N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine
Solubility
DMSO (~5 mg/ml) or H2O (~ 5 mg/ml)
Shipping Conditions
RT
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