Description
A breakdown product of JAK3 Inhibitor-IV (Cat. No. 420121) with similar inhibitory potency (pIC50 = 6.8 for JAK3; 5.0 for EGF-R; 4.7 for JAK1). Also inhibits STAT-5 phosphorylation and T-cell proliferation.
Abbr
JAK3 Inhibitor V(JAK3, EGFR, JAK1)
Alias
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Synonyms
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Targets
JAK-3, EGF-R, JAK1
Molecular Formula
C13H10O
Chemical Name
(2-Naphthylvinyl Ketone), ZM 449829