Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
IWP-3
Cat No.
CEI-0615
Description
An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro ( IC50 = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC₅₀ = 1.2 µM).
Alias
Inhibitor of Wnt Production-3
Appearance
Off-white solid
Product Overview
An inhibitor of Wnt production
CAS No.
687561-60-0
Molecular Weight
211.22
Purity
>98%
Storage
-20 centigrade
Synonyms
Inhibitor of Wnt Production-3
Targets
phosphatsae
Molecular Formula
C22H17FN4O2S3
Chemical Name
2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2- d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide
Solubility
DMSO (10 mg/ml)
Shipping Conditions
Gel pack
Download
Download Datasheet