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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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Cat No.

CEI-0549

Description

Cell-permeable. A histone demethylase (HDM) JMJD nhibitor. Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50s = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 µM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling.

Appearance

White solid

Product Overview

Histone demethylase JMJD inhibitor

CAS No.

5852-78-8

Molecular Weight

415.28

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

KDM6B, KDM3A, KDM4A, KDM4E, KDM4C

Molecular Formula

C 10 H 7 NO 3

Chemical Name

8-Hydroxy-5-quinolinecarboxylic acid; 8-Hydroxy-5-quinolinecarboxylic acid

Solubility

H₂O (20 mM) and MeOH (5 mg/ml)

Shipping Conditions

Gel pack