Description
Specific inhibitor of cRaf-1 kinase (IC50=9 nM). Acts at > 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective activity. Cell permeable.
Alias
3-(3, 5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1, 3-dihydro-indol-2-one
Appearance
Off white powder
Product Overview
c-Raf1 inhibitor
Purity
98% (TLC); NMR (Conforms)
Synonyms
3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one
Molecular Formula
C15H8Br2INO2
Solubility
May be dissolved in DMSO (50 mg/ml)
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