Description
GPLG0634 is a novel inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively in vitro.
Abbr
GPLG0634(JAK1, JAK2 )
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
JAK1A, JAK1B, JTK3
Molecular Formula
C21H23N5O3S
Chemical Name
Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,
4]triazolo[1,5-a]pyridin-2-yl]-
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL