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Gossypol
Cat No.
CEI-0361
Description
Gossypol
CAS No.
303-45-7
Molecular Weight
518.56
Purity
>99%
Storage
2 years at -20centigrade Powder
Targets
BCL2
Molecular Formula
C30H30O8
In vitro
Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. It has proapoptotic properties, probably due to the regulation of the Bax and Bcl2. It also reversibly inhibits calcineurin and binds to calmodulin. It inhibits replication of the HIV-1 virus. It is an effective protein kinase D inhibitor. It also causes low potassium levels, and thus causes temporary paralysis.
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