Description
Cell-permeable. Blocks adipogenesis by inhibiting the activation of SREBPs (Sterol Regulatory Binding Proteins). Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Prevents increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice.
Appearance
White to off-white solid
Product Overview
A Sterol Regulatory Binding Proteins (SREBPs) inhibitor
Molecular Formula
C 18 H 18 N 2 S
Chemical Name
2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole
Solubility
DMSO (200 mg/ml) or EtOH (10 mg/ml with warming)
Shipping Conditions
Gel pack
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