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Everolimus (RAD001)

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Cat No.

CEI-0122

Description

Everolimus (RAD001) can inhibit FKBP12 with IC50 of 1.6-2.4 nM.

Alias

Certican, Zortress, Afinitor

CAS No.

159351-69-6

Molecular Weight

958.22

Purity

>99%

Storage

2 years at -20centigrade Powder

Synonyms

Certican, Zortress, Afinitor

Targets

mTOR

Molecular Formula

C53H83NO14

Chemical Name

23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv

Solubility

DMSO 30 mg/mL Water

In vitro

As an mTOR inhibitor, everolimus (RAD001) can FKBP12 with IC50 of 1.6-2.4 nM. RAD001 inhibits tumor cell growth directly, blocks angiogenesis, and suppresses the immune response.