Description
Requires cytochrome P-450. Catalyses three sucessive oxidations of ent-kaurenoic acid. The second step includes a ring-B contraction giving the gibbane skeleton. In pumpkin (Cucurbita maxima) ent-6α,7α-dihydroxykaur-16-en-19-oate is also formed.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Reaction
ent-kaur-16-en-19-oate + 3 NADPH + 3 H+ + 3 O2 = gibberellin A12 + 3 NADP+ + 4 H2O (overall reaction); (1a) ent-kaur-16-en-19-oate + NADPH + H+ + O2 = ent-7α-hydroxykaur-16-en-19-oate + NADP+ + H2O; (1b) ent-7α-hydroxykaur-16-en-19-oate + NADPH + H+ + O2 = gibberellin A12 aldehyde + NADP+ + 2 H2O; (1c) gibberellin A12 aldehyde + NADPH + H+ + O2 = gibberellin A12 + NADP+ + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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