Description
A potent, irreversible inhibitor of human neutrophil elastase (HNE). The structure of the enzyme-inhibitor complex reveals crosslinking of the catalytic residues His-57 and Ser-195 by the peptidyl chloromethylketone.
Alias
MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone; MeOSuc-AAPA-CMK
Appearance
White to off-white solid
Product Overview
A potent, irreversible human leukocyte elastase (HLE) inhibitor
Synonyms
MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone; MeOSuc-AAPA-CMK
Molecular Formula
C₂₀H₃₁ClN₄O₇
Solubility
DMSO (20 mg/ml)
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