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Ebselen
Cat No.
CEI-0544
Description
An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC50 of 5.17 µM.
Appearance
White solid
Product Overview
A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
CAS No.
60940-34-3
Molecular Weight
292.12
Purity
>98% by TLC
Storage
-20 centigrade
Targets
KDM5B
Molecular Formula
C 13 H 9 NOSe
Chemical Name
2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
Solubility
DMSO (25 mg/ml)
Shipping Conditions
Gel pack
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