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Dynasore

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Cat No.

CEI-0470

Description

Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small GTPases. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addition

Appearance

Off-white solid

Product Overview

A potent dynamin inhibitor

CAS No.

304448-55-3

Molecular Weight

235.24

Purity

>98% by HPLC

Storage

-20 centigrade

Targets

DNM

Molecular Formula

C₁₈H₁₄N₂O₄ . H₂O

Chemical Name

3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide

Solubility

DMSO (>25 mg/ml)

Shipping Conditions

Gel pack