Description
A cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs). Treatment of cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.
Alias
2, 6-Diaminopyridine-3, 5-bis(thiocyanate), 3, 5-Dithiocyanatopyridine-2, 6-diamine
Appearance
White to off-white solid
Product Overview
A deubiquitinylating enzymes (DUB) inhibitor
Synonyms
2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine
Molecular Formula
C 7 H 5 N 5 S 2
Chemical Name
2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine
Solubility
DMSO (~10 mg/ml)
Shipping Conditions
Gel pack
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