Description
A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.
Alias
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Appearance
White to Off-white Solid
Product Overview
A hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH) inhibitor
Synonyms
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Molecular Formula
C 6 H 9 NO 5
Solubility
DMSO (5 mg/ml) or EtOH (0.5 mg/ml)
Shipping Conditions
Gel Pack
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