Description
DPP7 is essential for maintaining lymphocytes and fibroblasts in G (0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53. DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.
Abbr
DPP7, Recombinant (Human)
Applications
Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymph ocytes. DPP7 is used to study the regulation of cell quiescence. Like DPP4, DPP7 may be useful in diabetes and vascular disease research.
Product Overview
Contains amino acids 29 to end with a C-terminal His tag, MW=89.1 kDa
Form
Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 130 mM NaCl, 0.05% Tween-20, 10% glycerol
Enzyme Commission Number
EC 3.4.14.-
Molecular Weight
89.1 kDa
Unit Definition
One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25°C
Synonyms
EC 3.4.14.-; DPP7; Quiescent cell proline dipeptidase; Dipeptidyl Peptidase VII; DPP VII
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