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CUDC-101
Cat No.
CEI-0505
Description
A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
Appearance
Off-white solid
Product Overview
A potent inhibitor of HDACs and receptor tyrosine kinases
CAS No.
1012054-59-9
Molecular Weight
821.82
Storage
-20 centigrade
Targets
HDAC
Molecular Formula
C₂₄H₂₆N₄O₄
Chemical Name
7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide
Solubility
DMSO
Shipping Conditions
Gel pack
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