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Creatine Kinase MB Isoenzyme Type-2 from Human, Recombinant

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Cat No.

NATE-0819

Description

CK-MB Type II possesses the naturally occurring carboxy-terminal amino acid lysine. This occurs during a myocardial infarct (MI or heart attack) when CK-MB Type II is released from damaged heart muscle, and the C-terminal lysine is cleaved in the blood stream, thus creating CK-MB Type I. This difference can be exploited in diagnosis of an MI.

Abbr

CKMBT2, Recombinant (Human)

Alias

CKMBT2; CKMBITII; CKMBII; CKMB

Source

Pichia Pastoris

Species

Human

Appearance

Sterile Filtered colourless liquid formulation.

Product Overview

CKMBITII Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MB Isoenzyme in ELISA. The CKMBITII is purified by proprietary chromatographic techniques.

Activity

892 IU/mg

Purity

Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Stability

CKMBITII although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.

Buffer

Each mg of protein contains 20mM Tris-HCl, pH-6.8, 1mM EDTA and 1mM DTT.

Synonyms

Creatine Kinase MB Isoenzyme Type-II; Creatine Kinase MB Isoenzyme Type-2; CKMBT2; CKMBITII; CKMBII; CKMB

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NATE-1887	Native Mouse Creatine Kinase MM			Mouse Skeletal Muscle	Inquiry
NATE-1885	Native Human Creatine Kinase BB	EC 2.7.3.2	9001-15-4	Human Brain	Inquiry
NATE-1884	Native Porcine Creatine Kinase	EC 2.7.3.2	9001-15-4	Porcine Heart	Inquiry
NATE-1883	Native Human Creatine Kinase MM	EC 2.7.3.2	9001-15-4	Human Skeletal Muscle	Inquiry

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