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Cobimetinib (R-enantiomer)
Cat No.
CEI-1289
Product Overview
GDC-0973 (XL-518) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.
CAS No.
934660-94-3
Molecular Weight
531.31
Purity
0.98
Storage
Store at -20°C
Synonyms
GDC-0973 R-enantiomer; XL-518 R-enantiomer
Targets
MEK
Molecular Formula
C21H21F3IN3O2
Chemical Name
[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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