Product Overview
GDC-0973 (XL-518; GDC 0973) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.
Synonyms
GDC-0973 racemate; XL-518; GDC 0973; XL 518; GDC0973; XL518
Molecular Formula
C21H21F3IN3O2
Chemical Name
[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request