Description
Cell-permeable. A potent, competitive, and reversible antagonist of the orphan receptor GPR35 (Ki = 12.8 nM). Prevents the GPR35-mediated increase in ERK1/2 phosphorylation and β-arrestin recruitment induced by pamoic acid.
Product Overview
A potent and reversible antagonist of the orphan receptor GPR36
Molecular Formula
C₁₇H₁₉F₂N₅O₂S
Chemical Name
Methyl -5-((2-t-butylcarbamothioyl)hydrazono)methyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate
Solubility
DMSO (~25 mg/ml) or EtOH (~ 6 mg/ml)
Shipping Conditions
Gel pack
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