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Cathepsin K from Human, recombinant

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Cat No.

NATE-1705

Description

Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis.

Abbr

CTSK, Recombinant (Human)

Source

E. coli

Species

Human

Form

Liquid

Enzyme Commission Number

EC 3.4.22.38

Activity

>900 mU/mg protein

CAS No.

94716-09-3

Purity

> 95% by SDS-PAGE

Unit Definition

One unit is defined as the amount of enzyme that will hydrolyze 0.4 µmol Z-FR-AMC per min at 37°C, pH 5.5.

Storage

at –80°C. Avoid freeze/thaw

Synonyms

CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1703	Cathepsin K from Rat, recombinant	EC 3.4.22.38	94716-09-3	E. coli	Inquiry
NATE-1704	Cathepsin K from Mouse, recombinant	EC 3.4.22.38	94716-09-3	E. coli	Inquiry