Description
A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.)
Alias
Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
Product Overview
A Caspase-8 inhibitor
Synonyms
Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
Molecular Formula
C₃₀H₄₃FN₄O₁₁
Solubility
H₂O (50 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-FMK
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