Description
A synthetic peptide inhibitor that inhibits caspase-10 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-AEVD-FMK, Caspase-10 Inhibitor (fluoromethylketone)
Appearance
Yellowish brown solid
Product Overview
A caspase-10 inhibitor
Synonyms
Z-AEVD-FMK, Caspase-10 Inhibitor (fluoromethylketone)
Molecular Formula
C₂₈H₃₉N₄O₁₀F
Solubility
Ethanol (~50 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK