Description
BMS-2 is a potent MET kinase inhibitor with an IC50 value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC50 values of 4nM and 27nM respectively.
Abbr
BMS-2(MET, FLT3, KDR)
Alias
AUTS9, HGFR, RCCP2, c-Met
Product Overview
MET kinase, Flt-3 and VEGFR-2 kinases inhibitor,
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
AUTS9, HGFR, RCCP2, c-Met
Targets
Met, Flt-3, VEGFR-2
Molecular Formula
C25H16F2N4O3
Chemical Name
N-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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