Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
BML-277
Cat No.
CEI-0960
Description
A highly selective inhibitor of Chk2 (IC50=15 nM). Displays <25% inhibition of 35 other kinases at 10 uM). It possesses potent radioprotective activity and prevents apoptosis of human T-cells subjected to ionizing radiation (EC50= 3-7.6 μM). It is a useful tool for determining the role of Chk2 in cellular signaling.
Abbr
BML-277(CHEK2)
Alias
2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide, Chk2 Inhibitor II
Appearance
Off white solid
Product Overview
CHK2 inhibitor
CAS No.
516480-79-8
Molecular Weight
363.8
Purity
>98% (TLC; 1:1 ethylacetate: hexane; Rf=0.17); NMR (Conforms)
Synonyms
2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide, Chk2 Inhibitor II
Targets
CHK2
Molecular Formula
C20H14ClN3O2
Solubility
May be dissolved in DMSO (20 mg/ml); or Ethanol (20 mg/ml)
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-0122 | Checkpoint Kinase 2, Active Human, Recombinant | E. coli | Inquiry |