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Beta-Secretase Inhibitor II
Cat No.
CEI-0703
Description
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 µM) in CHO cells stably transfected with wild-type APP751.
Appearance
White solid
Product Overview
A beta-secretase inhibitor
Molecular Weight
588.56
Purity
>98% by HPLC
Storage
-20 centigrade
Targets
BACE1
Molecular Formula
C₂₅H₃₉N₃O₅
Solubility
DMSO ( 25 mg/ml)
Shipping Conditions
RT
Amino Acid Sequence
Z-Val-Leu-Leu--CHO
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