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Bayer-18

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Cat No.

CEI-1130

Description

Bayer-18 is a selective TYK2 inhibitor, with an IC50=18.7nM on TYK2. The compound shows 1000 fold selectivity against JAK2, CDK and KDR.

Abbr

Bayer-18(TYK2)

Alias

JTK1

CAS No.

1251752-12-1

Molecular Weight

390.46

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

JTK1

Targets

TYK2

Molecular Formula

C19H27FN6O2

Chemical Name

1-tert-butyl-3-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethyl-ethyl)amino]pyrimidin-2-yl]amino]phenyl]urea

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL