Description
AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with IC50 of 0.422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with IC50 of 0.322nM.
Alias
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Targets
Thr308/AKT, Ser473/AKT
Molecular Formula
C22H21N3O
Chemical Name
6-(4-(1-aminocyclobutyl)phenyl)-5-phenylnicotinamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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