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AV-412
Cat No.
CEI-1086
Description
AV-412 is an orally bioavailable dual kinase inhibitor with potential antineoplastic activity. It binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2).
Abbr
AV-412(EGFR, ERBB2)
Alias
ERBB, ERBB1, HER1, PIG61, Mena
Product Overview
Inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2)
CAS No.
451492-95-8
Molecular Weight
507
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
-20 centigrade
Synonyms
ERBB, ERBB1, HER1, PIG61, Mena
Targets
EGFR, HER2
Molecular Formula
C27H28ClFN6O
Chemical Name
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl)quinazolin-6-yl)acrylamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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