Description
An anti-arthritic drug that inhibits various leukocyte activation pathways at multiple sites. Inhibits release of inflammatory mediators from human basophils, pulmonary mast cells and macrophages. Also inhibits human neutrophil 5-lipoxygenase. Inhibits IκB kinase (IKK) by modifying Cys179 of the IKKß subunit. Efficient inducer of mitochondrial membrane permeability transition via the inhibition of mitochondrial thioredoxin reductase (TrxR).
Product Overview
Leukocyte activation pathways inhibitor
Targets
Leukocyte activation pathways
Molecular Formula
C20H34AuO9PS
Chemical Name
1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate
Shipping Conditions
Gel pack
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