Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
AS-604850
Cat No.
CEI-0100
Description
AS-604850
CAS No.
648449-76-7
Molecular Weight
285.22
Purity
>99%
Storage
2 years at -20 centigrade
Targets
PI3K-gamma
Molecular Formula
C11H5F2NO4S
Solubility
No
In vitro
AS-604850 is capable of inhibiting C5a-mediated PKB phosphorylation in RAW264 mouse macrophages with an IC50 with 10 uM. AS-604850 blocks MCP-1-mediated chemotaxis in Pik3cg +/+ monocytes in a concentration- dependent manner, with an IC50 of 21 mM, but dosnt affect chemotaxis in Pik3cg-/- cells, indicating that AS-604850 acts through PI3K-gamma.
Download
Download Datasheet