Description
A selective PI 3-Kgamma isoform inhibitor (IC50 = 0.24, 1.45, 0.07 and 1.70 uM for alpha, beta, gamma and delta isoforms respectively). Blocks neutrophil recruitment and displays anti-inflammatory activity. Active in vivo.
Alias
1. 5-Benzo[1, 3]dioxol-5-ylmethylene-thiazolidine-2, 4-dione
Product Overview
PI3Kgamma Inhibitor
Purity
>98% (TLC); NMR (Conforms)
Synonyms
1. 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione
Molecular Formula
C11H7NO4S
Solubility
May be dissolved in DMSO (25 mg/mL)