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Antithrombin III from Human
Cat No.
CEI-1597
Description
Antithrombin III is found in normal serum at 15 mg per 100 ml. Found at higher levels in plasma than in serum because of complexing with thrombin during coagulation. Functions in the inhibition of the proteolytic enzymes involved in blood coagulation and fibrinolysis, including factor Xa, plasmin, thrombin, and trypsin. Potency is strongly enhanced by heparin. Clinically, reduced levels are indicative of hypercoagulability.
Source
Human Plasma
Species
Human
Form
Lyophilized from 50 mM Tris-HCl, pH 8.0, with 150 mM NaCl.
CAS No.
90170-80-2
Molecular Weight
58000
Purity
>=95% by SDS-PAGE
Stability
> 1 year
Storage
<= -20°C
Synonyms
ATIII; Antithrombin; AT; Factor Xa inhibitor; Heparin cofactor
Extinction coefficient
0.65
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