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Angiostatin K1-3, human recombinant
Cat No.
CEI-0404
Description
Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED₅₀ =70 nM) relative to kringles 1-4 (ED₅₀ = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth
Alias
Angiostatin K1-4, Angiostatin Kringles 1-4, Angiostatin
Appearance
White solid
Product Overview
A specific inhibitor of endothelial cell growth and angiogenesis
Molecular Weight
1651.8
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
Angiostatin K1-3, Angiostatin Kringles 1-3, Angiostatin K1-3 human
Targets
Angiogenesis
Solubility
DMSO
Shipping Conditions
Gel pack
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