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Anastrozole
Cat No.
CEI-0349
Description
Anastrozole
Alias
Arimidex
CAS No.
120511-73-1
Molecular Weight
293.37
Purity
>99%
Storage
2 years at -20centigrade Powder
Synonyms
Arimidex
Targets
Aromatase
Molecular Formula
C17H19N5
Solubility
DMSO 59 mg/mL, Water
In vitro
Anastrozole inhibits the enzyme aromatase, which is responsible for converting androgens to estrogens. Anastrozole binds reversibly to the aromatase enzyme through competitive inhibition. Elevated levels of estrogens may increase the severity of breast cancer, as sex hormones can cause hyperplasia and differentiation at estrogen receptor sites. Anastrozole is used to treat breast cancer after surgery and for metastases in post-menopausal women.
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