Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
AminoAcylase-1 from Human, Recombinant
Cat No.
NATE-0810
Description
Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.
Abbr
ACY1, Recombinant (Human)
Alias
ACY1
Source
E. coli
Species
Human
Appearance
Sterile Filtered clear solution.
Product Overview
ACY1 Recombinant Human produced in E. coli is a single, non-glycosylated polypeptide chain containing 428 amino acids (1-408 a.a.) and having a molecular mass of 48 kDa. The ACY1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Molecular Weight
48 kDa
Purity
Greater than 90.0% as determined by SDS-PAGE.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Buffer
The ACY1 solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.
Synonyms
N-acyl-L-amino-acid amidohydrolase; ACY-1, ACY1D; ACYLASE; ACY1; aminoacylase 1; aminoacylase I; dehydropeptidase II; histozyme; hippuricase; benzamidase; acylase I; hippurase; amido acid deacylase; L-aminoacylase; acylase; aminoacylase; L-amino-acid acylase; α-N-acylaminoacid hydrolase; long acyl amidoacylase; short acyl amidoacylase
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1835 | L-Aminoacylase (Crude Enzyme) | EC 3.5.1.14 | 9012-37-7 | E. coli | Inquiry |
| NATE-0029 | Native Aspergillus melleus Acylase I | EC 3.5.1.14 | 9012-37-7 | Aspergillus melleus | Inquiry |
| NATE-0030 | Acylase I from Aspergillus sp., Immobilized on Eupergit C | EC 3.5.1.14 | 9012-37-7 | Aspergillus sp | Inquiry |
| NATE-0031 | Native Porcine Acylase I | EC 3.5.1.14 | 9012-37-7 | Porcine kidney | Inquiry |