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Amidepsine D, Humcola sp.
Cat No.
CEI-0458
Description
An inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50 = 17.5 µM) and Raji cells (IC50 = 2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Appearance
White to off-white solid
Product Overview
A diacylglycerol acyltransferase (DGAT) inhibitor
CAS No.
79786-34-8
Molecular Weight
366.24
Purity
>95% by HPLC
Storage
-20 centigrade
Targets
DGAT1
Molecular Formula
C 26 H 24 NO 10
Chemical Name
N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoic acid
Solubility
DMSO
Shipping Conditions
Gel pack
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