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Amidepsine A, Humcola sp.
Cat No.
CEI-0457
Description
A diacylglycerol acyltransferase (DGAT) inhibitor. Shows inhibitory effect in rat liver microsomes (IC50 = 10.2 µM) and Raji cells (IC50 = 15.5 µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Appearance
White solid
Product Overview
A diacylglycerol acyltransferase (DGAT) inhibitor
CAS No.
169181-28-6
Molecular Weight
266.33
Purity
>97% by HPLC
Storage
-20 centigrade
Targets
DGAT1
Molecular Formula
C 29 H 29 NO 11
Chemical Name
N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoyl]-L-alanine
Solubility
DMSO (10 mg/ml) or EtOH
Shipping Conditions
Gel pack
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