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AMG-47a
Cat No.
CEI-1083
Description
AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.
Abbr
AMG-47a(LCK)
Alias
RP4-675E8.4, LSK, YT16, p56lck, pp58lck
Product Overview
Inhibitor of Lck and T cell
CAS No.
882663-88-9
Molecular Weight
535.56
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
-20 centigrade
Synonyms
RP4-675E8.4, LSK, YT16, p56lck, pp58lck
Targets
Lck
Molecular Formula
C29H28F3N5O2
Chemical Name
3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)-4-methylbenzamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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