Description
AMG-25 exhibits potent inhibition of c-Kit with greater than 200-fold selectivity against KDR, p38, Lck and Src, and possesses desirable pharmacokinetic properties.
Alias
C-Kit, CD117, PBT, SCFR
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
C-Kit, CD117, PBT, SCFR
Molecular Formula
C23H17N5O2
Chemical Name
3-(2-aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl) pyridin-2(1H)-one
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL