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AMG-208

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Cat No.

CEI-0034

Description

AMG-208

CAS No.

1002304-34-8

Molecular Weight

383.4

Purity

>99%

Storage

2 years at -20 centigrade

Targets

c-Met

Molecular Formula

C22H17N5O2

Solubility

In vitro

As a selective inhibitor, AMG-208 can potently inhibit c-Met with IC50 of 9.3 nM. In PC3 cells, AMG-208 also can induce inhibition to c-Met phosphorylation mediated by HGF with IC50 of 46 nM.